Reusable 3D-printing ink shows promise for gabapentin tablets

Researchers in Finland and Sweden reported that a reusable, gelatin-based ink can support on-demand 3D printing of personalized gabapentin tablets for veterinary patients, at least under some conditions. In the Frontiers in Veterinary Science study, the team printed two gabapentin formulations using a proprietary gelatin-based excipient, CuraVet®, then reused the same syringe after 14 days of refrigerated storage. The lower-concentration formulation kept its printability and dosing precision without changing printer settings, while the higher-concentration version developed crystals, suggesting stability limits for more concentrated preparations. The authors said the lower-dose tablets could be produced in under 30 minutes with little hands-on work. (frontiersin.org)

Why it matters: Personalized dosing remains a practical challenge in small animal medicine, especially for drugs like gabapentin that are often compounded or adapted from human products because there are few, if any, marketed veterinary formulations in some settings. Earlier work has already shown semi-solid extrusion 3D printing can produce tailored gabapentin chewable tablets, and newer stability research in veterinary printlets has emphasized that storage, repeat use, and quality control are likely to determine whether this technology can move from proof of concept into routine pharmacy or clinic workflows. For veterinary professionals, the takeaway is that reusable inks could reduce prep time and waste, but only if practices can validate formulation stability, dose uniformity, and handling procedures for each product. (sciencedirect.com)

What to watch: The next step is whether follow-on studies can show longer storage stability, broader drug compatibility, and a clearer regulatory path for point-of-care veterinary printing. (sciencedirect.com)

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